Epidemiological analysis for Hereditary Angioedema Disease V8.1

• Research type

  Research Study

• Full title

  EHA - Epidemiological analysis for Hereditary Angioedema Disease(EHA Study) AN INTERNATIONAL, MULTICENTER, EPIDEMIOLOGICAL PROTOCOL

• IRAS ID

  252391

• Contact name

  Matt Reed

• Contact email

  Matthew.Reed@nhslothian.scot.nhs.uk

• Sponsor organisation

  Centogene AG

• Duration of Study in the UK

  4 years, 0 months, 1 days

• Research summary

  This study is looking at whether a new Dried Blood Spot (DBS) filtercard is useful in the Emergency Department (ED) and General Practice (GP) to screen for the prevalence of Hereditary Angioedema (HAE) in patients with undiagnosed repetitive abdominal pain or angioedema. Participation in the study involves a standard history, examination, and taking of a single research blood sample. This single research blood sample will be equivalent to 18 drops of blood (around 4mls/one teaspoon). This will be applied to the Dry Blood Spot (DBS) filtercard which will be sent for biochemical and genetic analysis at Centogene laboratory in order to diagnose Hereditary Angioedema Disease (HAE) type I/II.

• REC name

  South East Scotland REC 01

• REC reference

  18/SS/0140

• Date of REC Opinion

  3 Dec 2018

• REC opinion

  Further Information Favourable Opinion