EORTC 1508

  • Research type

    Research Study

  • Full title

    A phase II study of the anti-PDL1 antibody atezolizumab, bevacizumab and acetylsalicylic acid to investigate safety and efficacy of this combination in recurrent platinum-resistant ovarian, fallopian tube or primary peritoneal adenocarcinoma.

  • IRAS ID

    211576

  • Contact name

    Susana Banerjee

  • Contact email

    Susana.Banerjee@rmh.nhs.uk

  • Sponsor organisation

    European Organisation For Research and Treatment of Cancer (EORTC)

  • Eudract number

    2015-004601-17

  • Clinicaltrials.gov Identifier

    NCT02659384

  • Duration of Study in the UK

    4 years, 2 months, 1 days

  • Research summary

    Summary of Research

    This study tests a new drug, both in combination with a known treatment and alone, in people with recurrent ovarian, fallopian tube or primary peritoneal cancer. The purpose is to find out whether the drug atezolizumab (the new drug) and combinations of atezolizumab with bevacizumab (the known drug) works against these cancers and/or is safe. The study will also look at giving acetylsalicylic acid (aspirin) together with these treatments as there is some evidence to suggest that it may help the two drugs work better.

  • REC name

    London - Fulham Research Ethics Committee

  • REC reference

    17/LO/0985

  • Date of REC Opinion

    21 Jul 2017

  • REC opinion

    Further Information Favourable Opinion