Energy restriction by exercise or diet on bone, muscle and cognition
Research type
Research Study
Full title
Effects of short-term energy restriction achieved by diet or exercise on bone turnover, muscle function and cognition.
IRAS ID
154899
Contact name
Craig Sale
Contact email
Sponsor organisation
Nottingham Trent University
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
It is well established that energy restriction can have negative effects on various physiological systems, as non-essential processes are sacrificed in an attempt to preserve energy for the most vital functions of the body. The level and the duration of the energy restriction dictates the response, with more pronounced effects observed during severe or prolonged periods of energy restriction. Many populations regularly undertake periods of energy restriction including athletes, military recruits and obese patients and it is important that the responses to energy restriction are understood in order to minimise any associated negative outcomes. Bone health, cognitive function and muscle function are all considered fundamental to health, quality of life, performance and injury prevention, and may be compromised during periods of energy deficiency. Energy restriction can be induced via increased energy expenditure, reduced dietary intake or a combination of both, however it is not currently known whether the method by which the energy deficit is achieved affects bone, muscle and cognitive function. Examining the same level of energy restriction induced by diet or exercise alone may provide the answer to this fundamental question.
REC name
East Midlands - Derby Research Ethics Committee
REC reference
14/EM/1156
Date of REC Opinion
17 Oct 2014
REC opinion
Further Information Favourable Opinion