EMR Biobank (Renewal)
Research type
Research Tissue Bank
IRAS ID
317135
Research summary
Experimental Medicine and Rheumatology Biobank (EMR Biobank), Queen Mary University of London
REC name
West of Scotland REC 4
REC reference
22/WS/0147
Date of REC Opinion
12 Dec 2022
REC opinion
Further Information Favourable Opinion
Data collection arrangements
Synovial tissue, Cartilage, Bone (either as a result of specific biopsy or a surplus of joint replacement operation)
Whole blood and isolated blood cell subsets
Urine
Stool (Faeces) to investigate microbioma composition
Synovial Fluid [obtained as per clinical indications e.g. arthrocentesis for diagnostic (gout, infection) and or treatment intervention (flare of arthritis)]
DNA
RNA
Saliva
Skin
Hair
Salivary gland (SG) samples (surplus from diagnostic labial or major SG biopsies) lymph node/spleen biopsy/tissue, kidney biopsies and other solid tissue related to disease
Surplus tissue from interventional or diagnostic procedures e.g. tonsils (tonsillectomy), bone marrow, lymph nodes peripheral nerves and brain biopsies
Cerebral Spinal fluid (CSF) collected during routine lumbar puncture/surgery due to spinal traumaResearch programme
The EMR Biobank will support research in the following areas - inflammatory and musculoskeletal diseases including: RA and inflammatory arthritis, Sjogren's, SLE, connective tissue diseases, vasculitis, OA, hard and soft tissue injuries (such as meniscal lesion, chondral defects and ligament and tendon injury), immunological and genetic mechanisms of disease. The research will involve identification of tissue and peripheral blood biomarkers of disease evolution and response to treatment and multi-omic analyses.
Storage license
12199
RTBTitle
Experimental Medicine and Rheumatology Biobank (EMR Biobank), Queen Mary University of London
Establishment organisation
Centre for Experimental Medicine & Rheumatology, Queen Mary University of London
Establishment organisation address
William Harvey Research Institute, 2nd Floor John Vane Science Centre
Charterhouse Square
London
EC1M 6BQ