EMPIRIC

  • Research type

    Research Study

  • Full title

    An Exploratory study of using Magnetic resonance Prognostic Imaging markers for Radiotherapy In patients with Cervix cancer (EMPIRIC)

  • IRAS ID

    299186

  • Contact name

    Yat Man Tsang

  • Contact email

    yatmantsang@nhs.net

  • Sponsor organisation

    East and North Hertfordshire NHS Trust

  • Duration of Study in the UK

    4 years, 0 months, 1 days

  • Research summary

    Patients with cervical cancer that has not spread to other parts of the body can be cured with radiotherapy. One of the reasons radiotherapy can fail is because there are areas within the tumour that have a poor oxygen supply which makes them resistant to radiotherapy. This study aims to assesss if it is feasible using special types of magnetic resonance imaging (MRI) - multi-parametric (MP) MRI to identify areas of low oxygen within the tumour so a higher dose of radiation can be given specifically to these areas to overcome the resistance and potentially improve cure rates without increasing side effects.

  • REC name

    London - Fulham Research Ethics Committee

  • REC reference

    21/PR/1756

  • Date of REC Opinion

    9 Feb 2022

  • REC opinion

    Further Information Favourable Opinion