ELORAS

  • Research type

    Research Study

  • Full title

    Explaining Language Outcome And Recovery After Stroke

  • IRAS ID

    265430

  • Contact name

    Cathy J. Price

  • Contact email

    c.j.price@ucl.ac.uk

  • Sponsor organisation

    University College London

  • Duration of Study in the UK

    7 years, 9 months, 31 days

  • Research summary

    Aphasia (difficulty producing and/or comprehending speech) severely impairs quality of life and renders stroke survivors prone to social isolation, dependence and depression. In the UK alone, one person every 15 minutes will have a stroke and be left with aphasia, but there is currently no way for their clinicians to know whether, when or how they will recover their speech and language skills. The challenge we face is that patients can have very different recovery trajectories even when they have seemingly similar baseline language impairments, brain lesions and therapy input. Unpredictable recovery makes it difficult for patients and their carers to plan their future (e.g. their return to work). Moreover, the inability to predict how patients will recover in the absence of treatment makes it difficult to establish baselines against which to compare the efficacy of therapeutic interventions. The aim of this project is to provide a theoretical model that explains and predicts aphasia and its recovery after stroke. The theoretical model will explain whether, when and how much a patient is likely to recover their speech and language abilities after stroke.

  • REC name

    London - South East Research Ethics Committee

  • REC reference

    19/LO/1755

  • Date of REC Opinion

    27 Jan 2020

  • REC opinion

    Further Information Favourable Opinion