Ejaculatory dysfunction after BPH surgery: retrograde or Anejaculation
Research type
Research Study
Full title
Is Ejaculatory Dysfunction Following Surgical Management of BPH/LUTS Truly Retrograde Ejaculation
IRAS ID
166334
Contact name
Reza Razavi
Contact email
Sponsor organisation
King's College Hospital NHS Foundation Trust
Duration of Study in the UK
0 years, 7 months, 27 days
Research summary
Medical and surgical treatment for men with benign prostatic enlargement (BPH) and/or lower urinary tact symptoms (LUTS) often lead to ejaculatory dysfunction with reduced volume ejaculate or dry orgasms. For a long time this had been thought to be due to backwards flow of semen into the bladder (retrograde ejaculation) resulting from disruption of the tissue at the bladder neck. Recent evidence suggests an intact bladder neck is not essential to the antegrade flow of semen. By quantitative analysis of sperm cells in post orgasm urine samples of patients with reduced ejaculation following the most common operations to treat BPH/LUTS the aim of this study is to establish whether there truly is retrograde ejaculation. This understanding will support the development of anatomical ejaculation preserving surgical techniques.
REC name
Yorkshire & The Humber - Leeds West Research Ethics Committee
REC reference
15/YH/0147
Date of REC Opinion
2 Apr 2015
REC opinion
Favourable Opinion