Efficacy LSPT to identify pregnancy 64-70 days

  • Research type

    Research Study

  • Full title

    Efficacy of a low-sensitivity urine pregnancy test (LSPT) for identifying ongoing pregnancy after medical abortion at 64 to 70 days of gestation

  • IRAS ID

    248370

  • Contact name

    Patricia Lohr

  • Contact email

    patricia.lohr@bpas.org

  • Sponsor organisation

    British Pregnancy Advisory Service

  • Duration of Study in the UK

    1 years, 6 months, 2 days

  • Research summary

    Early medical abortion involves taking two types of medication (mifepristone and misoprostol) in order to end a pregnancy. One to two weeks after taking the medications, follow-up to assess abortion completion is done in clinic via exam, ultrasound, and/or urine or blood testing. In addition, remote follow-up has been shown to be successful using a low-sensitivity urine pregnancy test (LSPT). Current British Pregnancy Advisory Service (BPAS) policy allows women having medical abortion through 63 days gestation to opt for follow-up via ultrasound or via remote self-administration of a LSPT and a screening questionnaire. Under BPAS policy, women between 64-70 days are required to return to the clinic for ultrasound evaluation. While this policy serves to avoid false negative results that might delay treatment of an ongoing pregnancy, it adds an extra burden for women in this gestational age range. There is insufficient data on the sensitivity of the LSPT this gestational age, but if test has high sensitivity, BPAS policy could be revised to allow remote follow-up for this group of women as well. We aim to evaluate the ability of an LSPT to identify women with ongoing pregnancy during medical abortion at 64 to 70 days of gestation.

  • REC name

    West Midlands - Solihull Research Ethics Committee

  • REC reference

    18/WM/0288

  • Date of REC Opinion

    17 Oct 2018

  • REC opinion

    Further Information Favourable Opinion