Effects of Ramadan fasting in patients with type 2 diabetes
Research type
Research Study
Full title
The effects of Ramadan fasting on the metabolic parameters in type 2 diabetes among children and young adults.
IRAS ID
270250
Contact name
Hala Elmajnoun
Contact email
Sponsor organisation
De Montfort University
Duration of Study in the UK
1 years, 9 months, 30 days
Research summary
This research study explores the impacts of Ramadan fasting (RF) on the metabolic parameters (blood biomarkers) in patients with type 2 diabetes (T2D) among children and young adults, and in healthy individuals (12 to 24 years old). The effects of RF on the metabolic parameters in T2D among adults has been extensively researched in recent years. Some studies found that RF has positive impacts on human health, such as; it helps to decrease body weight, and it improves blood glucose biomarkers in healthy people and in patients with diabetes. However, other research studies found that RF had no/minimum influence on human health and it might increase the hypoglycaemic events in T2D. These effects have not been studied in children/ young adults with T2D yet, and to date, no study has looked specifically at the effects of RF on these groups in the UK. Therefore, it is essential to carry out research studies among these groups of the population, as it might reveal significant effects of fasting and dietary patterns during Ramadan on the blood biomarkers. The outcome from this study will provide evidence to whether RF is safe and good for them and it could be used as a therapeutic intervention among these individuals and decrease disease progression, or whether it's better to avoid fasting in order to prevent any risks on their health. The interested participants will be recruited from several locations in the UK including children’s hospitals, endocrine clinics, diabetic centres, general practitioners (GPs) and community centres (schools, youth clubs, and De Montfort University (DMU)). The study design will involve a questionnaire and blood samples collection and these activities will be taking place at three different points of time (three visits), before, during and after Ramadan, the study will last for around 2 months.
REC name
East of England - Cambridge South Research Ethics Committee
REC reference
19/EE/0342
Date of REC Opinion
20 Nov 2019
REC opinion
Unfavourable Opinion