Effects of hospitalisation on acute exacerbations of airways disease

  • Research type

    Research Study

  • Full title

    Establishing the feasibility and value of studying acute exacerbations of airway disease in the context of admission to hospital



  • Contact name

    Andrew Wardlaw

  • Contact email


  • Sponsor organisation

    University of Leicester

  • Duration of Study in the UK

    1 years, 4 months, 30 days

  • Research summary

    Hospitalisation for exacerbations of airways disease- asthma and chronic obstructive pulmonary disease (COPD)- are important events in the natural history of the disease and recognised as imperative points for potential intervention. Readmission to hospital is common (COPD is the largest cause of hospital readmission in the UK), and suggests more rapid downward trajectory.
    The response to hospitalisation and recovery are heterogenous, and good markers to inform longer term outcome are unknown. This observational study aims to identify risk factors for hospital readmission and different response to clinical treatment.
    Patients with underlying asthma or COPD who are admitted to the University Hospitals of Leicester with an exacerbation of asthma or COPD will be recruited. Measures will then be performed within the Hospital Trust and Leicester Respiratory Biomedical Research Unit at Glenfield Hospital.
    Participants will be followed up for one year, with measures performed during their hospital admission and following recovery at 6 weeks.

  • REC name

    London - City & East Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    8 Dec 2015

  • REC opinion

    Further Information Favourable Opinion