Effects of 100mg Hydrocortisone injection into Deltoid & Thigh
Research type
Research Study
Full title
An Open Label, Non-Randomised study to investigate the effects of 100mg Intramascular Hydrocortisone Injection in the Deltoid and Upper Thigh Muscle during the state of hypocortisolaemia
IRAS ID
156100
Contact name
Phillip Yeoh
Contact email
Sponsor organisation
NMC
Eudract number
2015-001090-40
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
An Open Label, Non-Randomised study to investigate the effects of 100mg Intramascular Hydrocortisone Injection in the Deltoid and Upper Thigh during the state of hypocortisolaemia
Our current recommendation for patients with adrenal insufficiency when unwell is to self inject intramuscularly with 100mg hydrocortisone to prevent patient developing adrenal crisis. The most common site for injection is thigh muscle. We would like to demonstrate injecting into deltoid muscle is as effective as injecting into the thigh muscle. We also want to compare the pain level when injecting with Efscortesol® versus Solu-Cortef® hydrocortisone preparations as well as using the orange 1" in the deltoid muscle versus blue 1¼" in the thigh muscle.REC name
London - Hampstead Research Ethics Committee
REC reference
15/LO/0749
Date of REC Opinion
22 Jun 2015
REC opinion
Further Information Favourable Opinion