Effect of vasospasm on non-invasive intracranial pressure measurement.
Research type
Research Study
Full title
The effect of vasospasm on non-invasive intracranial pressure measurement.
IRAS ID
218934
Contact name
AA Birch
Contact email
Duration of Study in the UK
0 years, 10 months, 26 days
Research summary
When a person has a bleed inside the skull from a weakened artery in their brain, it can have life threatening consequences if not quickly and effectively managed. Two potential side effects of this type of brain injury are; increased pressure inside the skull and restriction of blood flow though arteries in the brain. Prolonged, increased pressure inside the skull can cause compression of the brain and possibly death. Restriction of blood flow can result in parts of the brain not receiving enough oxygen. Resolution of these two side effects therefore requires close monitoring and rapid intervention. Recently, methods of measuring increased pressure inside the skull have been developed. These methods incorporate blood flow measuring medical devices placed outside the skull to determine the pressure, differing from typical methods that require devices to be placed inside the skull. As these methods of measurements are based on blood flow characteristics, they may potentially be vulnerable to inaccuracy; if blood flow is altered due to side effects of the initial injury. This project will therefore investigate, if any, the effects of altered blood flow velocity on the accuracy of pressure measurement inside the skull using the newly developed methods mentioned.
REC name
South Central - Berkshire Research Ethics Committee
REC reference
17/SC/0538
Date of REC Opinion
25 Oct 2017
REC opinion
Favourable Opinion