Effect of spiral artery remodelling on the placenta

  • Research type

    Research Study

  • Full title

    Spiral artery remodelling in normal and pre-eclamptic pregnancy (SPAR) - Southampton Study

  • IRAS ID

    125810

  • Contact name

    Rohan Lewis

  • Contact email

    rml2@soton.ac.uk

  • Sponsor organisation

    University of Southampton

  • Research summary

    Summary: NONE

    Lay summary of study results:

    We analysed gene expression in the placentas as intended, but the study did not produce informative results. The primary issue was that when the samples were unblinded, it became apparent that the groups were not well-matched in terms of gestational age, making interpretation of the data difficult.

  • REC name

    West Midlands - Coventry & Warwickshire Research Ethics Committee

  • REC reference

    13/WM/0184

  • Date of REC Opinion

    26 Apr 2013

  • REC opinion

    Favourable Opinion