Effect of socioeconomic status on compliance with management v1
Research type
Research Study
Full title
Investigating the role of education and socioeconomic status on compliance with medical advice and risk factor management in patients with peripheral arterial disease
IRAS ID
198483
Contact name
Abigail Morbi
Contact email
Sponsor organisation
Imperial College
Duration of Study in the UK
0 years, 3 months, 30 days
Research summary
Peripheral arterial disease is highly prevalent, affecting 16.9% men and 20.5% women aged 55 and above. The most severe manifestation of peripheral arterial disease is critical limb ischaemia, which can result in limb-threatening morbidity and mortality. Patients with critical limb ischaemia will be referred to a vascular surgeon, for consideration of endovascular or surgical management; the aim of this being to prevent limb loss.
A number of factors predict risk of poor outcomes in this cohort, in part relating to the fact that they are a co-morbid population, with a high prevalence of cardiovascular disease and diabetes. Medication compliance, exercise therapy and smoking cessation are important in modifying cardiovascular risk factors and reducing the risk of complications and death. However, not all patients comply with these measures and many continue to have poor outcomes. Evidence suggests socioeconomic status and patient education may affect compliance.
The aim of this study is to understand the effect of socioeconomic status on patient compliance with medical and lifestyle management in patients with critical limb ischaemia. This study will be carried out over a 3 month period, with patients recruited from vascular clinics at St Mary's Hospital, Paddington. Patients will be asked to fill in a questionnaire, to ascertain level of education, socioeconomic status and compliance. The questionnaire will also explore reasons for non-compliance and patient ideas on how this could be improved. Exclusion criteria: patients <18years of age and those who are unable to give consent or understand English.
Statistical analysis will be undertaken to correlate patient factors (e.g. socioeconomic status) with patient-reported compliance. Based on these findings and patient-reported reasons for non-compliance, we will design an intervention to improve patient compliance with management for critical limb ischaemia.
REC name
East Midlands - Nottingham 2 Research Ethics Committee
REC reference
16/EM/0092
Date of REC Opinion
7 Mar 2016
REC opinion
Further Information Favourable Opinion