Effect of Multi injections of Elamipretide on Patients with Chronic HF

• Research type

  Research Study

• Full title

  A Phase 2 Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Effects of Multiple Subcutaneous Injections of Elamipretide on Left Ventricular Function in Subjects with Stable Heart Failure with Reduced Ejection Fraction

• IRAS ID

  201904

• Contact name

  Jim Carr

• Contact email

  Jim.Carr@stealthbt.com

• Eudract number

  2014-005724-10

• Duration of Study in the UK

  1 years, 0 months, 30 days

• Research summary

  This research study is designed to determine if multiple subcutaneous injections of the study drug at different doses; has any effect on heart function in patients with chronic heart disease; is safe to take; how well it can be tolerated
  This study will also:
  Investigate how much of the study drug gets into the blood stream
  Assess whether the study drug has an impact on quality of life
  Explore the effects of the study drug on a certain component of the blood, called N-terminal pro-brain natriuretic peptide NT-pro-BNP, which may indicate how well the heart is working

• REC name

  South Central - Hampshire B Research Ethics Committee

• REC reference

  16/SC/0275

• Date of REC Opinion

  9 Aug 2016

• REC opinion

  Further Information Favourable Opinion