Effect of high intensity exercise on metabolism and insulin response
Research type
Research Study
Full title
Effect of high intensity-low volume (HI-LV) sprint interval exercise on 22 hour metabolism and insulin sensitivity.
IRAS ID
181326
Contact name
Fiona Gribble
Contact email
Sponsor organisation
Joint CUHNFT and the University of Cambridge
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Endurance exercise is one of the most effective approaches to increase glucose tolerance and prevent development of type 2 diabetes. Acutely, endurance exercise can increase metabolic rate by 5 to 10-fold and prolonged high intensity exercise may reduce plasma glucose. Metabolism is not only influenced during exercise; improved glucose tolerance and increased insulin sensitivity have been observed more than 24 h after an acute bout of exercise. Exercise recommendations advise 30 min of daily moderate intensity exercise. However, many do not reach these recommendations and a common reason is lack of time. Recently high intensity training has been suggested as a time-saving alternative to prolonged endurance training to improve fitness and metabolic health. High intensity low volume (HI-LV) is performed as 30 seconds sprints of maximal intensity repeated 4-6 times, and such training has been shown to improve insulin sensitivity and reduce body weight. The mechanisms by which such a small amount of work can increase glucose tolerance remain unknown. The aim of this pilot study is to establish the effect of HI-LV exercise in ten participants, on insulin sensitivity, energy expenditure and other gut hormones responses.
REC name
East of England - Cambridge East Research Ethics Committee
REC reference
16/EE/0256
Date of REC Opinion
27 Jul 2016
REC opinion
Further Information Favourable Opinion