Effect of exercise intervention on oxidative stress_Version 2.1
Research type
Research Study
Full title
The effect of a bespoke home based exercise intervention on markers of oxidative stress and markers of general health, in older adults receiving care.
IRAS ID
184162
Contact name
Sarah Aldred
Contact email
Sponsor organisation
University of Birmingham
Duration of Study in the UK
0 years, 5 months, 28 days
Research summary
Physical activity is important for health. If older adults receiving care in their own homes are physically active, they may benefit from improved quality of life, improved sleep quality, reduced behavioural disturbance and a reduction in biomarkers of disease.
Oxidative stress is seen to a limited extent in healthy aging, and to a greater extent in diseases associated with aging. The aim of this study is to assess the effect of increased physical activity on biomarkers of oxidative stress and markers of health in a group of home-dwelling older adults receiving daily care provided by Care Companions (a professional care service based in Sutton Coldfield). Our central hypothesis is that increasing physical activity will reduce markers of oxidative stress and improve markers of health in cared for older adults. We aim to test this hypothesis by comparing the effect of 6-week home based exercise training in older adults receiving daily care to another group who will continue their normal routine.
The main strengths of this study are: the objective measure of physical activity using an activity sensor; the opportunity to incorporate an increase in physical activity into daily care already being administered to this group of older adults and; the potential to improve health and physical functioning to allow prolonged home-dwelling.
REC name
East Midlands - Nottingham 1 Research Ethics Committee
REC reference
15/EM/0296
Date of REC Opinion
30 Sep 2015
REC opinion
Further Information Favourable Opinion