Effect of cognitive training on cognitive function in type 2 diabetes
Research type
Research Study
Full title
Investigating the effect of a computerised cognitive training intervention on cognitive function in type 2 diabetes mellitus
IRAS ID
227672
Contact name
Ffion Curtis
Contact email
Sponsor organisation
University of Lincoln
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Investigating the effect of a cognitive training intervention on cognitive function in type 2 diabetes mellitus
Ageing is naturally associated with a decline in the functioning of the human brain. It is suggested that this process is accelerated in type 2 diabetes mellitus (T2DM) increasing the risk of dementia. Cognitive decline and dementia represent very important public health problems that impact the ability to maintain social function and independent living. Thus, it is important to identify strategies to help improve the accelerated cognitive decline associated with T2DM. Cognitive training interventions have previously been shown to be effective in improving cognitive function within healthy cohorts. However, evidence is limited in a T2DM population. Therefore, It is important to further explore the effects of a cognitive training intervention in a T2DM population. The aim of this study is to investigate the effect of a computerised cognitive training intervention on cognitive function in T2DM.
A randomised controlled trial study design will be used to investigate the effect of a cognitive training intervention on cognitive function in T2DM. Individuals diagnosed with type 2 diabetes mellitus will be randomly allocated into either a cognitive training group or usual care group. Individuals randomised to the cognitive intervention arm will complete 12 hours of computerised cognitive training over a 4-6 weeks period. Cognitive sessions will last approximately 60 minutes and will be performed 2-3 times a week and will be conducted either at the University of Lincoln or in the participant's home. Individuals allocated to the usual care group will continue with usual care only. Outcome measurements including cognitive function, brain derived neurotropic factor, and feasibility measurements will be measured pre and post intervention, with glycated haemoglobin being measured at pre-intervention only.
REC name
East Midlands - Leicester Central Research Ethics Committee
REC reference
18/EM/0125
Date of REC Opinion
12 Jun 2018
REC opinion
Further Information Favourable Opinion