Effect of APT cycling on Multiple Sclerosis
Research type
Research Study
Full title
The effect of cycling using active-passive trainers on spasticity, cardiovascular fitness, function and quality of life in people with Multiple Sclerosis.
IRAS ID
200448
Contact name
Lorna Paul
Contact email
Sponsor organisation
University of Glasgow
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
Exercise is beneficial for people with Multiple Sclerosis (pwMS) however exercise options for those with moderate to high levels of disability are limited. Cycling, delivered with an Active Passive Trainer (APT) is one exercise option often offered within rehabilitation/exercise settings and many pwMS buy APT’s for home use. Anecdotally pwMS report they feel better and their spasticity reduces after APT cycling, however there is a lack of evidence to support this. \n\n30 pwMS will be recruited from the Physical Disability Rehabilitation Unit at the Queen Elizabeth University Hospital and randomised to APT + usual care or usual care only. Those in the APT group will receive 30 minutes of APT (2 mins passive warm up, 26 mins active cycling and 2 mins passive cool down), five days per week for 4 weeks. Outcome measures will be cardiovascular fitness measured using the oxygen uptake efficiency slope (OUES), spasticity assessed by Modified Ashworth Scale (MAS) and the Multiple Sclerosis Spasticity Scale (MSSS-88), function assessed by the Functional Independence Measure (FIM) and the Timed 25 foot walk test (T25FW), Quality of Life measured by MSQOL-54. Outcome measures will be assessed in both groups before and after the 4 week intervention period. Symmetry, distance cycled and power will be recorded following each cycling session in the intervention group.
REC name
West of Scotland REC 5
REC reference
16/WS/0084
Date of REC Opinion
26 Apr 2016
REC opinion
Favourable Opinion