Echocardiography, CT and MRI in congenital heart disease version 1
Research type
Research Database
IRAS ID
304329
Contact name
John Simpson
Contact email
Research summary
Echocardiographic, MRI and CT image databases (currently provided by Philips Intellispace Cardiovascular (ISCV) and Sectra PACS)
REC name
London - Westminster Research Ethics Committee
REC reference
21/LO/0650
Date of REC Opinion
20 Oct 2021
REC opinion
Further Information Favourable Opinion
Data collection arrangements
All cardiac imaging data in our institution are currently stored on specifically designed databases - echocardiographic data (currently Philips ISCV) and CT/MRI data (currently Sectra PACS). The systems store scans and patient identifiers to locate the scans: name, date of birth, hospital number and NHS number. No other patient details are held on these systems. These are password-protected systems consistent with Guy's and St Thomas' (GSTT) information governance policies. We do not propose performing any additional scans which are not clinically necessary, nor collecting any more patient information than is already collected. The database is currently available to all members of the paediatric cardiology clinical healthcare team at Evelina Children's Hospital. The only researchers who will have access to the database will be members of the clinical healthcare team, and members of the clinical research team from King's College London who are affiliated with GSTT and are approved to access patient records. We may share some information with our imaging scientist colleagues within King's Health Partners, but any images shared beyond the clinical healthcare team will not contain patient identifiers and will be pseudo-anonymised with a key code which will be stored on a password-protected computer in a locked office.
Research programme
The databases are already in existence for use for clinical purposes. We propose for members of the clinical research team to access these databases for research purposes. We propose to use the data retrospectively for research into novel imaging modalities in congenital heart disease. This includes the 3D Heart Project, an extended reality software system which has been designed to assist with pre-procedural planning in this context. Prior to using this system prospectively in the clinical setting, we wish to perform validation using retrospectively-collected multi-modality (3D echo, CT and MRI) imaging data. This imaging data will be useful for ensuring adequate visualisation of anatomical structures, efficacy of specific tools including zoom, crop and rotate, and ensuring that measurements made within the system are reliable and in-keeping with measurements made using standard imaging platforms. Research which utilises images from the database typically involves patients, parents and other stakeholders. Previous and current research supported by NIHR and BHF has closely involved relevant stakeholders to design and inform research direction.
Research database title
Echocardiographic, MRI and CT image databases (currently provided by Philips Intellispace Cardiovascular (ISCV) and Sectra PACS)
Establishment organisation
Evelina London Children's Hospital
Establishment organisation address
Westminster Bridge Road
London
SE1 7EH