Early Intervention Mission
Research type
Research Study
Full title
Early Intervention in Psychosis Mental Health Mission Cohort
IRAS ID
333754
Contact name
Graham Murray
Contact email
Sponsor organisation
Cambridgeshire and Peterborough NHS Foundation Trust and the University of Cambridge
Duration of Study in the UK
3 years, 5 months, 31 days
Research summary
We aim to develop a longitudinal representative study that will allow researchers to identify ways to help earlier identification, treatment and prevention of emerging psychosis patients. Patients who have had at least one episode of psychosis or identified as being at risk of psychosis will be invited to participate in the study. Controls will also be recruited.
Participants will be invited to give a blood sample, and a researcher will ask them questions from a set of questionnaires. Patients (but not controls) will also be asked to complete questionaires via electronic means (online or via a phone app once launched). They will answer these questions shortly after their initial appointment and at least every six months for a duration of up to 3 years.
If participants are unable to give blood (e.g. for clinical reasons) then saliva may be used instead. If patients do not have access to a smartphone or wish not to use the phone app on their personal phone (once launched), then with agreement with the researcher, the researcher may take on the responsibility of inputting the app data on the patient’s behalf. If patients do not enter information at the six-monthly interval, a researcher may get in touch with them to remind them.
Participants are welcome to withdraw at any point in the study. A full explanation of how their data is managed is provided in the Participant Information Sheet. They may be asked the reason(s) for their withdrawal to improve future studies.
By participating, participants will allow researchers to learn more about the genetic sequence, chemical makeup, protein makeup, and the body’s natural defence system, to facilitate new research to drive improvements in the early diagnosis and treatment of psychosis. This will allow future studies to drive forward preventive approaches and new treatments.REC name
West Midlands - Edgbaston Research Ethics Committee
REC reference
24/WM/0133
Date of REC Opinion
30 Jul 2024
REC opinion
Further Information Favourable Opinion