Early-EDGE Registry
Research type
Research Study
Full title
Early discharge after mitral and tricuspid edge-to-edge repair: an assessment of feasibility and safety
IRAS ID
318352
Contact name
Sam Dawkins
Contact email
Sponsor organisation
Department of Cardiology, John Radcliffe Hospital
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Mitral regurgitation (MR) and tricuspid regurgitation (TR) are common causes of breathlessness, fluid retention and other heart failure symptoms, which lead to reduced quality of life and frequent hospitalisation. These conditions are particularly prevalent in older adults with many of these patients being at high risk for for surgical intervention due to frailty and co-morbidities, leaving them with few treatment alternatives.
Transcatheter edge-to-edge repair (TEER) procedures have increasingly been used to improve the severity of both MR and TR, offering patients symptomatic relief and reductions in heart failure hospitalisation at low procedural risk. There is considerable geographic variation in protocols to assess these patients prior to the procedure and also in length of hospital stay. The standard of care in the UK, and particularly in Oxford, emphasises fewer investigations before the TEER procedure and shorter length of hospital stay.
This prospective, observational cohort study will examine the safety and feasibility of this practice.
REC name
East Midlands - Leicester South Research Ethics Committee
REC reference
23/EM/0038
Date of REC Opinion
27 Feb 2023
REC opinion
Favourable Opinion