Early detection of lung cancer using a spectroscopic liquid biopsy

  • Research type

    Research Study

  • Full title

    Early detection of lung cancer using a spectroscopic liquid biopsy.

  • IRAS ID

    349449

  • Contact name

    David Palmer

  • Contact email

    david.palmer@dxcover.com

  • Sponsor organisation

    Dxcover Ltd

  • Clinicaltrials.gov Identifier

    n/a, n/a

  • Duration of Study in the UK

    0 years, 11 months, 31 days

  • Research summary

    Serum and/or plasma from blood samples from approximately 6500 patients taken from the iDx Lung cohort will be sent to Dxcover Ltd in Glasgow, Scotland, who will analyse them by Fourier-Transform Infra-red Spectroscopy in order to develop a machine learning model for the early detection of lung cancer. The samples and data will be fully anonymised with identifiable patient data removed. Spectroscopy is a low-resolution technique that does not reveal genome sequence or any other characteristics of the samples that could be used to identify patients.

  • REC name

    London - Queen Square Research Ethics Committee

  • REC reference

    25/PR/1481

  • Date of REC Opinion

    21 Jan 2026

  • REC opinion

    Further Information Favourable Opinion