Dyslexia Genetics
Research type
Research Study
Full title
Case study of the genetics of developmental dyslexia
IRAS ID
89128
Contact name
John F Stein
Contact email
Sponsor organisation
University of Oxford
Duration of Study in the UK
4 years, 11 months, 31 days
Research summary
We wish to continue studies to identify the human genetic variations that confer susceptibility to reading problems (developmental dyslexia). The Dyslexia Research Trust (DRT) and the grant for Dr Paracchini's fellowship will fund this project. We will seek volunteers from children and adults with dyslexia who attend our reading disability clinics in Reading and Oxford to donate saliva and allow us to measure their phenotypic sensory, cognitive and reading abilities. Their DNA markers will then be compared with these measures by Prof Paracchini in St Andrew's University. These studies will also allow us to better define the phenotype of dyslexia by determining whether the orthographic and phonological skills required to learn to read fluently are separately inherited or if there are common underlying neurodevelopmental factors, and to investigate the relationships between these genetic variations and the basic visual, auditory and motor processes that underlie reading.
REC name
North of Scotland Research Ethics Committee 1
REC reference
14/NS/1022
Date of REC Opinion
18 Jul 2014
REC opinion
Further Information Favourable Opinion