Dynamic Patient-Specific Modelling in Structural Heart Intervention
Research type
Research Study
Full title
The Application of Dynamic Patient-Specific Modelling in Structural Heart Intervention
IRAS ID
277842
Contact name
Apurva Bharucha
Contact email
Sponsor organisation
King’s College Hospital NHS Foundation Trust
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Heart valves prevent back flow (regurgitation) of blood during any given heartbeat (cardiac cycle). The mitral valve is the primary inlet valve for the left side of the heart which is responsible for a large portion of the heart’s output. Mitral Regurgitation is the commonest heart valve problem for which open heart surgical repair is the treatment of choice. More recently, mitral valve repair can be achieved by delivery of repair devices via skin puncture of a large sized blood vessel for patients in whom surgery is considered too risky-this technique is known broadly as transcatheter mitral valve repair.
Our team have developed a bench top heart simulator which allows simulation of patients’ mitral valve pathologies using 3D printing techniques. This study tests the ability of our heart simulator to predict outcomes in patients with severe mitral regurgitation undergoing mitral valve repair and whether it would be useful as a training aid for surgeons/cardiologists before they perform the procedure
REC name
London - Dulwich Research Ethics Committee
REC reference
21/LO/0023
Date of REC Opinion
10 Feb 2021
REC opinion
Further Information Favourable Opinion