Dupuytren's In SoCiety Outcomes (DISCO)
Research type
Research Study
Full title
Prevalence, progression and impact of Dupuytren's disease on patients in society.
IRAS ID
203741
Contact name
Jagdeep Nanchahal
Contact email
Sponsor organisation
University of Oxford
Clinicaltrials.gov Identifier
n/a, n/a
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
Prevalence, progression and impact of Dupuytren's disease on patients in society
Dupuytren's disease (DD) is a common condition which causes the fingers to gradually curl into the palm so they can no longer be straightened. There are currently no effective treatments for early stage disease to slow or prevent progression. Due to this lack of effective early treatment, patients with early disease are not routinely seen or monitored in primary or secondary care, and there is a profound lack of knowledge about Dupuytren's disease in its early stage.
Participants will be adults with Dupuytren’s disease at any stage, they will be identified through GP records, advertising and online media to ensure a broad range of disease stages are researched.
The study will use simple questionnaires and self-taken hand photographs at six-monthly intervals to assess disease stage and monitor progression over a year. Participants are not required to travel for the study as all involvement can be done remotely.
We aim to improve our understanding of how prevalent Dupuytren's disease is, and the proportion of people living with early disease. We will monitor disease progression over a year and assess how well participants can judge their own stage of disease and progression. We will use standardised measures of general health to assess the impact of Dupuytren's disease at different stages.
REC name
East of England - Essex Research Ethics Committee
REC reference
16/EE/0349
Date of REC Opinion
16 Aug 2016
REC opinion
Favourable Opinion