(duplicate) Bath Spondyloarthritis Biobank

• Research type

  Research Tissue Bank

• IRAS ID

  248375

• Research summary

  The Bath Spondyloarthritis (SpA) Biobank

• REC name

  South West - Central Bristol Research Ethics Committee

• REC reference

  18/SW/0141

• Date of REC Opinion

  6 Sep 2018

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  Demographic information (including GP details, ethnicity, age, education, employment, gender) \nClinical assessments (including symptoms, other diagnosis, x-rays, MRI, past medical history, medications, disease activity, symptom onset), family history, \nmetrology measurements, \nBlood samples (Serum / DNA / Plasma) \nPatient reported questionnaires (including pain, fatigue, work, comorbidity and quality of life and exercise) \nAdditional health risks (fractures and osteoporosis etc), and other relevant clinical information (including previous treatment). Informed consent will be taken in writing and stored in secure research facility and in patients’ notes.

• Research programme

  Patients with spondyloarthritis (an arthritis particularly affecting the spine, but may also have other manifestations) can develop profound symptoms that limit mobility and quality of life. Over time, some patients also develop changes to the bones of the spine, which can further restrict movement. We would like to better understand why some patients develop these features but others do not, and using blood biomarkers is a promising way of learning more about the disease process.

• RTBTitle

  The Bath Spondyloarthritis (SpA) Biobank

• Establishment organisation

  The Royal National Hospital for Rheumatic Diseases, Royal United Hospital NHS Foundation Trust

• Establishment organisation address

  Upper Borough Walls

  Bath

  BA1 1RL