DRUID (DRessing of diabetic foot Ulcers; Infection Deterrent) trial
Research type
Research Study
Full title
Investigation of different dressing strategies for diabetic foot ulcers to minimise risk of infection; a prospective, randomised, controlled, feasibility clinical trial
IRAS ID
250770
Contact name
Shona Johnston
Contact email
Sponsor organisation
Cumbria Partnership NHS Foundation Trust
Clinicaltrials.gov Identifier
CP18YY, CP18YY
Duration of Study in the UK
1 years, 2 months, 28 days
Research summary
Diabetic foot ulcers (DFU) can lead to infection and further deterioration to health. They are big burden on both the NHS and the patient. The management of DFUs is initially focuses on achieving wound healing. However, in many cases this objective is not met and chronic wound management then shifts its attention to avoiding infection and further complications. Clinicians have the option to treat the wound conservatively (non-antimicrobial dressings) or more aggressively (antimicrobial dressings to actively kill bacteria in the wound). At present there is a lack of data available to aid clinicians in deciding what approach is best. This study will explore if one approach is potentially better than the other in terms of reducing the risk of infection and promote wound healing. A non-antimicrobial dressing, a rotational regime of three different chemical-based antimicrobial dressings (honey, silver, iodine) and a physical antimicrobial dressing will be compared in patients over a trial period of 18 weeks per participant. In addition to recording the need to change wound management due to significant deterioration or improvement, patient and clinician satisfaction will be compared too, as will infection rates and wound healing outcomes
REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
18/NE/0330
Date of REC Opinion
17 Dec 2018
REC opinion
Further Information Favourable Opinion