Dose-Finding of lower limb mirror therapy after stroke.

• Research type

  Research Study

• Full title

  Maximum tolerable dose per day to do lower limb mirror therapy with ankle exercise after stroke.

• IRAS ID

  255913

• Contact name

  Sarah Bajuaifer

• Contact email

  s.bajuaifer@uea.ac.uk

• Sponsor organisation

  University of East Anglia

• Duration of Study in the UK

  2 years, 0 months, 1 days

• Research summary

  This study will investigate the maximum dose per day of using mirror therapy with ankle dorsiflexion exercise after stroke. Participants will be in the sub-acute stage after stroke. The design is a 3+3 rule based, dose- finding study. Each cohort will consist of Three participants.The first cohort will be assigned to do 15 minutes per day for two weeks.The second and subsequent cohorts will exercise at target dose set accordance to the nine preset rules and the modified Fibonacci sequence (mFBS).The study will continue until the stopping rule is triggered.The last dose tested that will be identified as the maximum tolerable dose per day.

• REC name

  London - Stanmore Research Ethics Committee

• REC reference

  19/LO/0422

• Date of REC Opinion

  23 Apr 2019

• REC opinion

  Further Information Favourable Opinion