Does SAP bind to NETs - a pilot study.
Research type
Research Study
Full title
Does serum amyloid P component bind to neutrophil extracellular traps - a pilot study.
IRAS ID
191842
Contact name
Simon Kolstoe
Contact email
Sponsor organisation
University of Portsmouth
Duration of Study in the UK
2 years, 11 months, 21 days
Research summary
Neutrophils are a type of white blood cell that play a role protecting the body from infection. In certain instances neutrophils can eject their own DNA forming sticky meshes that entrap bacteria. These meshes have only recently been discovered and are called Neutrophil Extracellular Traps (NETs). In this pilot study we are interested in determining whether a specific human immune protein binds to NETs. If it does bind this study will suggest additional immunological pathways are involved with NET function, forming the basis for future studies in a variety of disease states.
REC name
South Central - Oxford C Research Ethics Committee
REC reference
15/SC/0624
Date of REC Opinion
5 Oct 2015
REC opinion
Favourable Opinion