Does increasing morphine result in improved function in chronic pain?
Research type
Research Study
Full title
What is the relationship between increase in morphine dose and improvement in functional outcome in patients with chronic back pain
IRAS ID
174831
Contact name
Shiva Tripathi
Contact email
Sponsor organisation
Lancashire Teaching Hospitals NHS Foundation Trust
Duration of Study in the UK
0 years, 2 months, 13 days
Research summary
This study will explore the relationship between escalation of morphine dose and improvement in functional ability.
It will investigate the effect of increasing the dose of morphine in line with usual clinical practice, and if it leads to an improvement in baseline function. In addition it will explore whether improving pain will improve function.
Functional change will be assessed using both subjective and objective measurements - Oswentry Disability Index (ODI), Patient Specific Functional Scale (PSFS) and Modified Schober's Test (MST). The ViMove - a non invasive system used to measure body movements and understand their contribution to pain - will also be used to provide and objective measurement of movement. In addition, all patients will be asked to complete a short pain questionnaire (Brief Pain Inventory, BPI).
This is an important area of research which can help inform the practice of prescribing of morphine in chronic back pain patients.
REC name
South Central - Berkshire Research Ethics Committee
REC reference
15/SC/0307
Date of REC Opinion
21 May 2015
REC opinion
Further Information Favourable Opinion