Does Gut Permeability Alter after Gastric Bypass in Type 2 Diabetes?
Research type
Research Study
Full title
A pilot study to investigate whether the permeability of the intestinal mucosa is altered after Gastric Bypass surgery in patients with Type 2 diabetes.
IRAS ID
180750
Contact name
Christopher Pring
Contact email
Sponsor organisation
Sussex NHS Research Consortium
Duration of Study in the UK
0 years, 6 months, 1 days
Research summary
The levels of cholesterol in the blood are known to decrease after gastric bypass surgery and the reasons for this are unclear. However, how absorbent the gut is and hence how much cholesterol is absorbed, may account for the decrease in cholesterol levels in the blood. This study will use a standard gut permeability Nuclear Medicine test (51CrEDTA) to see how permeable a patient’s gut is before and after gastric bypass surgery. Only patients with Type 2 diabetes will be included.
REC name
South Central - Hampshire B Research Ethics Committee
REC reference
15/SC/0461
Date of REC Opinion
5 Nov 2015
REC opinion
Further Information Favourable Opinion