Does botulinum A toxin help with pain from rotator cuff arthropathy?
Research type
Research Study
Full title
Do ultrasound guided botulinum A injections relieve pain in rotator cuff arthropathy?
IRAS ID
171998
Contact name
Chris Smith
Contact email
Sponsor organisation
Royal Devon and Exeter NHS Foundation Trust
Eudract number
2015-002176-25
Clinicaltrials.gov Identifier
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
Rotator cuff arthropathy is a cause of shoulder arthritis which is a common condition seen both in primary and secondary care. It is a painful condition, with significant disability. Reverse shoulder replacements are a good option for this condition and have found acceptance nationally and internationally, although like any operation, they can be associated with complications. A potential alternative is the use of Botox injections, which have a significant cost saving (fifty fold) over a reverse total shoulder replacement. To date there have been no trials comparing the use of a botox injection for pain relief in cuff arthropathy. If there is a significant clinical difference in the pain outcomes after Botox injections, this could result in significant savings to the NHS and the taxpayer as a whole. If high levels of pain relief could be predictably obtained using Botulinum A toxin injections then potentially patients could avoid the need for surgery.
REC name
Wales REC 2
REC reference
16/WA/0007
Date of REC Opinion
12 Feb 2016
REC opinion
Further Information Favourable Opinion