Do statins increase sensitivity to glucagon? Version 1.0
Research type
Research Study
Full title
Do statins increase sensitivity to glucagon?
IRAS ID
198681
Contact name
Tricia Tan
Contact email
Sponsor organisation
Imperial College London
Eudract number
2016-002306-39
Duration of Study in the UK
1 years, 0 months, 1 days
Research summary
Statins are a group of drugs used to treat high cholesterol and reduce the risk of heart disease. A recently identified side effect of statins is that they can impair the body’s ability to regulate blood glucose (sugar), causing some people taking them to develop diabetes. The reason why this happens is not known at present.
One possibility is that statins might increase the body’s responsiveness to a naturally produced hormone called glucagon, which increases blood glucose levels. This study is is designed to investigate this possibility in humans, as if confirmed it could explain why statins cause diabetes.
REC name
London - West London & GTAC Research Ethics Committee
REC reference
16/LO/1452
Date of REC Opinion
31 Oct 2016
REC opinion
Further Information Favourable Opinion