DNA bank for genetic studies in idiopathic dystonia

• Research type

  Research Tissue Bank

• IRAS ID

  214677

• Research summary

  DNA bank for genetic studies in idiopathic dystonia

• REC name

  Yorkshire & The Humber - Leeds East Research Ethics Committee

• REC reference

  16/YH/0467

• Date of REC Opinion

  25 Jan 2017

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  This project involves the collection of 10ml blood samples, or if the patient prefers, buccal swabs, from patients with idiopathic dystonia and control participants with no history of dystonia. Demographic details and details of dystonia will be recorded for patients using a questionnaire. The samples and data from patients and controls will be collected at the Neurology clinic at the Royal Hallamshire Hospital to allow the extraction of DNA at Sheffield Hallam University in order to carry out studies that will increase the understanding of the genetic factors involved in dystonia.

• Research programme

  It is envisaged that small research groups at Sheffield Teaching Hospitals and Sheffield Hallam University may want to access this tissue bank in the future (including applications from outside the 2 organisations). Any applications will be made, reviewed and approved by a scientific advisory board, who will ensure the correct conduct of the research studies and release of data and samples is in accordance with the Research Governance framework and HTA regulations.

• Storage license

  12182

• RTBTitle

  DNA bank for genetic studies in idiopathic dystonia

• Establishment organisation

  Sheffield Teaching Hospitals NHS FT

• Establishment organisation address

  Royal Hallamshire Hospital, Clinical Research Office

  Sheffield

  S10 2JF