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  • Research type

    Research Study

  • Full title

    DIagnostic and Severity markers of COVID-19 to Enable Rapid triage (DISCOVER) study



  • Contact name

    David Arnold

  • Contact email

  • Sponsor organisation

    North Bristol NHS Trust

  • Duration of Study in the UK

    1 years, 0 months, 4 days

  • Research summary

    COVID-19 is a lung disease caused by a virus called SARS-CoV-2, commonly referred to as the coronavirus. The coronavirus has different effects on different people. Many people who get the infection get mild or no symptoms at all and do not require hospital care. Of those who do come to hospital, some will be able to go home but some will need to be admitted for medical treatment\nincluding oxygen therapy or mechanical ventilation (where a machine is required to help with breathing).\n\nDoctors and nurses are required to make decisions on how best to treat patients early. However, given COVID-19 is a new infection many of our usual tests have not been fully researched for patients with this virus. Also, there are several new tests that might be useful to healthcare professionals in diagnosing and managing this condition, but they also have not been fully tested.\n\nThe DISCOVER study aims to collect blood samples and medical information from patients with suspected coronavirus. These blood samples will be analysed for both routine and new tests. We will then follow people up at 1 month to see how coronavirus affected them and see how useful the blood tests were at predicting this. We hope to rapidly publish this work and share our results with other UK and international centres to allow wider use of successful prognostic biomarkers.\n\nBlood will also be stored (anonymously) for future research on how COVID-19 makes people ill. In the future, this information could help doctors decide which tests are useful in managing coronavirus and which are not.

  • REC name

    Yorkshire & The Humber - South Yorkshire Research Ethics Committee

  • REC reference


  • Date of REC Opinion

    27 Mar 2020

  • REC opinion

    Further Information Favourable Opinion