Digital Interventions in Neuro-Rehabilitation (DINR)

  • Research type

    Research Study

  • Full title

    Digital Interventions in Neuro-Rehabilitation: Two digital neuro interventions (DNIs)for word retrieval. The development and testing of two web-based therapy applications for people with naming difficulties caused by Stroke (iTALKbetter) or Mild-Moderate Dementia (Gotcha!).

  • IRAS ID

    227211

  • Contact name

    Alexander P Leff

  • Contact email

    a.leff@ucl.ac.uk

  • Clinicaltrials.gov Identifier

    Z6364106/2017/08/52 health research, UCL Data Protection Registration reference

  • Duration of Study in the UK

    0 years, 8 months, 1 days

  • Research summary

    The main aim is to develop and test clinical efficacy of two novel, web-based, rehabilitation applications funded by NIHR. iTALKbetter will provide an app-based therapy for people with naming difficulties caused by stroke (naming app for a wide variety of common words and phrases), while Gotcha! will be for patients with dementia (who have difficulty naming people they know well). These two digital neuro interventions (DNIs) will provide the opportunity for the necessary increased rehabilitation that help people recover lost function. This will alleviate NHS therapist (SALT) time and put patients in control of when and where the carry out practice-based language therapy.

    While both apps will be aimed at different patient populations, the underlying software and development pipelines are almost identical, hence our combining them here for the purposes of ethical review.

    Each app will go through three separate phases, each of which will require specific patient information sheets and formal consent: Phase 1 is development of the app (with patients as co-creators); the second phase is a standard, small-scale phase II clinical trial with randomized allocation of subjects; phase 3 is ‘roll-out’ where the app is made publicly available. We will continue to ask scientific questions about the real-world functioning of the app in this phase.

    This application seeks ethical approval for phase 1 only.

  • REC name

    London - Queen Square Research Ethics Committee

  • REC reference

    17/LO/1846

  • Date of REC Opinion

    10 Nov 2017

  • REC opinion

    Further Information Favourable Opinion