Dietary Intake in IBD, IBS and healthy controls
Research type
Research Study
Full title
A case-control study of dietary intake in patients with active and inactive inflammatory bowel disease and irritable bowel syndrome compared to healthy controls
IRAS ID
203156
Contact name
Selina Cox
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
Patients with inflammatory bowel disease have previously been shown to have altered nutritional intake, as well as being at increased risk of malnutrition. However, previous studies have used varying methods and groups of patients to understand nutritional intake in inflammatory bowel disease.
Many patients with inactive inflammatory bowel disease continue to experience gut symptoms which may include abdominal pain, bloating and diarrhoea, and which are not thought to be due to active gut inflammation. These symptoms may be worsened by the intake of a group of dietary carbohydrates ('fermentable' carbohydrates) and the dietary intake of these has recently been shown to be lower in patients with active inflammatory bowel disease. However, the reasons for reduced intake is unclear.Therefore the aim of this study is to investigate nutritional intake, including fermentable carbohydrates, in patients with active inflammatory bowel disease, inactive inflammatory bowel disease with and without gut symptoms, and patients with irritable bowel syndrome, compared to healthy controls.
Participants with inflammatory bowel disease will be recruited from gastroenterology services at two NHS trusts: Guy's and St Thomas NHS Foundation Trust and Barts Health NHS Trust. Dietary intake data for patients with IBS has previously been collected in a REC approved trial (REC reference: 12/LO/1402). Patients will be screened against inclusion and exclusion criteria if interest in taking part in the study. After providing written consent, eligible participants will be asked to complete a food frequency questionnaire and food-related quality of life questionnaire and the researcher will collect demographic information including age, gender, and ethnicity. They will then be asked to complete 7-day unweighed food records, which will either be posted back to the researcher or returned in person.
REC name
London - City & East Research Ethics Committee
REC reference
16/LO/0976
Date of REC Opinion
17 May 2016
REC opinion
Favourable Opinion