Dietary fibre supplementation in early prostate cancer
Research type
Research Study
Full title
Dietary fibre supplementation to delay disease progression in early prostate cancer (DEFINITE)
IRAS ID
340457
Contact name
Anne Kiltie
Contact email
Sponsor organisation
University of Aberdeen
Duration of Study in the UK
1 years, 6 months, 31 days
Research summary
This qualitative research study aims to explore the attitudes of prostate cancer patients on active surveillance (AS) towards dietary fibre supplementation, given the potential benefits demonstrated in previous research. Prostate cancer patients on AS, often overlooked in the literature, experience cyclical anxiety, particularly regarding disease progression. Lifestyle modifications, including dietary changes, are pursued by a number of these patients as a preventative measure. Dietary fibre such as inulin and psyllium have promising results in studies of pelvic cancers. However, it is important to note that these findings do not directly apply to patients who are currently undergoing AS for prostate cancer. Despite potential side effects, these dietary fibres may contribute to anti-inflammatory and anti-tumorigenic effects.
Building on this evidence, we aim to explore patient perspectives on the feasibility and acceptability of dietary fibre supplementation during AS. The insights gained will guide the development of a feasibility and/or pilot studies and, subsequently, a multicentre randomised controlled trial. If successful, this intervention could potentially reshape clinical practice for patients with prostate cancer on AS.
REC name
West Midlands - Coventry & Warwickshire Research Ethics Committee
REC reference
24/WM/0129
Date of REC Opinion
31 May 2024
REC opinion
Favourable Opinion