Diagnostic accuracy of clinical indicators to identify NP in LBLP
Research type
Research Study
Full title
Diagnostic accuracy of clinical indicators to identify neuropathic pain in Low Back Related Leg Pain
IRAS ID
358487
Contact name
Tim Noblet
Contact email
Sponsor organisation
St George's University Hospitals NHS Foundation Trust
Duration of Study in the UK
0 years, 6 months, 2 days
Research summary
This research aims to identify the most effective clinical tests for diagnosing neuropathic pain in low back related leg pain (sciatica). Neuropathic pain in low back related leg pain is a common condition that is often challenging to diagnose and treat accurately. Difficulties in diagnosis can lead to mismanagement, resulting in poorer patient outcomes.
In this study, we will evaluate a range of clinical indicators—including clinical examination questions, physical tests, and self-reported questionnaires—by comparing their results to MRI findings. The most accurate tests will be identified through subsequent analysis.
Participants will be adults presenting to the spinal clinic at St. George’s Hospital with suspected sciatica. They will undergo their routine clinical appointment, followed by an additional 30 minutes of research-focused testing of clinical indicators. No additional follow-up will be required. Participants will also undergo a scheduled MRI scan, which is part of their usual clinical care.
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
25/WM/0222
Date of REC Opinion
5 Nov 2025
REC opinion
Favourable Opinion