Development of a Mild Cognitive Impairment Core Outcome Set

  • Research type

    Research Study

  • Full title

    Development of a Mild Cognitive Impairment Core Outcome Set (MCI-COS)

  • IRAS ID

    325742

  • Contact name

    Nicholas Turner

  • Contact email

    nicholas.turner@bristol.ac.uk

  • Sponsor organisation

    University of Bristol

  • Clinicaltrials.gov Identifier

    2117, COMET Initiative registration

  • Duration of Study in the UK

    0 years, 8 months, 31 days

  • Research summary

    Mild cognitive impairment (MCI) is a condition where someone is experiencing worse cognitive (thinking and memory) problems than expected for their age, but they do not have dementia. People with MCI can still do their normal activities but may be forgetful and find it hard to learn new skills. People with MCI are at a high risk of developing dementia.

    We want to stop people with MCI from going on to get dementia, and improve the lives of people with MCI, yet we do not know how to show treatments work for people with MCI. To test new treatments, we need to know what people consider to be the most important things we should look at. Here we aim to find out what the most important things are for patients so that we can improve the help they get from doctors and improve how we test new drugs.

    We do not have national (e.g., NICE) guidelines to help people live well with MCI. Understanding what is important to people with MCI (and those who know them) will help us ask the right questions in clinic and can be used in research that really helps people.

    We will look at what researchers have done before to see what they focused on. Next, we will talk with people with MCI, their loved ones, health and social care professionals, policymakers, and academics, to explore opinions on what is important. Then, through a survey of these people and talking with these people, we will reach agreement on the most important outcomes.

  • REC name

    London - Queen Square Research Ethics Committee

  • REC reference

    23/PR/1580

  • Date of REC Opinion

    11 Jun 2024

  • REC opinion

    Further Information Favourable Opinion