Development and validation of Paediatric Severe Asthma Questionnaire
Research type
Research Study
Full title
Development and validation of the Paediatric Severe Asthma Questionnaire (PSAQ)
IRAS ID
309811
Contact name
Graham Roberts
Contact email
Sponsor organisation
University of Southampton
Duration of Study in the UK
0 years, 7 months, 7 days
Research summary
Development of a quality of life questionnaire for children and adolescents with severe asthma.
300 million people worldwide live with asthma. 1 in 20 people with asthma have severe, or harder to treat, asthma. Severe asthma can dramatically affect the lives of patients and their families and put pressure on healthcare services. The impact of severe asthma on children and adolescents in particular is not well understood, making treatment and management of symptoms challenging.
We aim to develop a questionnaire to measure how severe asthma affects young people’s everyday life, also known as ‘quality of life’ (QoL). The answers to the Paediatric Severe Asthma Questionnaire (PSAQ) will help doctors give the right support and treatment for patients to manage their asthma. The questionnaire will also allow young people to share their experiences of living with severe asthma and have a voice in the decisions about their treatment and care.
This study will involve children (10-17 years), and parents of children with severe asthma (6-17 years). Recruitment will be from secondary asthma clinics. Patient organisations such as European Federation of Allergy and Airways Diseases Patients' Associations and European Lung Foundation will provide publicity to support recruitment.
We will utilise a multi-stage process to develop the PSAQ:i) interviews and group discussions with children and parents (20-40 participants) to elicit:
• de novo QoL deficits for paediatric severe asthma;
• views about the suitability of the adult Severe Asthma Questionnaire for children.
ii) generate a list of ‘candidate’ questions for the novel questionnaire.
iii) field testing survey to select questions for the prototype PSAQ (100 participants).
iv) interviews to test the prototype PSAQ for relevance, wording, and comprehensiveness (20-40 participants).
v) interviews to pilot refined PSAQ (10-20 participants).
vi) survey to test whether the PSAQ is ‘valid’ i.e. good at measuring QoL (200 participants).REC name
London - Camden & Kings Cross Research Ethics Committee
REC reference
22/PR/0590
Date of REC Opinion
14 Jul 2022
REC opinion
Further Information Favourable Opinion