Detection of Pseudomonas aeruginosa in Cystic Fibrosis
Research type
Research Study
Full title
Non-invasive detection of Pseudomonas aeruginosa lower airway infection in patients with Cystic Fibrosis
IRAS ID
233578
Contact name
Jane C Davies
Contact email
Sponsor organisation
Impeiral College London
Clinicaltrials.gov Identifier
17/LO/1931, London Camberwell - St Giles research ethics committee
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
Cystic fibrosis (CF) is a severe, inherited disease leading to recurrent chest infections and lung damage. Pseudomonas aeruginosa (Pa) is the most common bacterial infection in patients with CF. If therapy is started quickly then we can usually clear the infection, and people may remain infection-free for months or years. Current detection methods rely on culture of sputum or cough swabs but diagnosis is not immediate and many people cannot even produce sputum in order to test for Pa. We would like to explore different tests to detect Pa using breath and other samples to see if we can detect and treat Pa sooner than what is currently available.
REC name
London - Camberwell St Giles Research Ethics Committee
REC reference
17/LO/1931
Date of REC Opinion
7 Jan 2018
REC opinion
Further Information Favourable Opinion