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Detection of Pseudomonas aeruginosa in Cystic Fibrosis

  • Research type

    Research Study

  • Full title

    Non-invasive detection of Pseudomonas aeruginosa lower airway infection in patients with Cystic Fibrosis

  • IRAS ID

    233578

  • Contact name

    Jane C Davies

  • Contact email

    j.c.davies@imperial.ac.uk

  • Sponsor organisation

    Impeiral College London

  • Clinicaltrials.gov Identifier

    17/LO/1931, London Camberwell - St Giles research ethics committee

  • Duration of Study in the UK

    2 years, 0 months, 0 days

  • Research summary

    Cystic fibrosis (CF) is a severe, inherited disease leading to recurrent chest infections and lung damage. Pseudomonas aeruginosa (Pa) is the most common bacterial infection in patients with CF. If therapy is started quickly then we can usually clear the infection, and people may remain infection-free for months or years. Current detection methods rely on culture of sputum or cough swabs but diagnosis is not immediate and many people cannot even produce sputum in order to test for Pa. We would like to explore different tests to detect Pa using breath and other samples to see if we can detect and treat Pa sooner than what is currently available.

  • REC name

    London - Camberwell St Giles Research Ethics Committee

  • REC reference

    17/LO/1931

  • Date of REC Opinion

    7 Jan 2018

  • REC opinion

    Further Information Favourable Opinion