Derivation of GMP Grade MSCs from Wharton's Jelly
Research type
Research Study
Full title
Derivation of GMP Grade MSCs from Wharton's Jelly
IRAS ID
252920
Contact name
Joanne Mountford
Contact email
Sponsor organisation
Scottish National Blood Transfusion Service
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
3 years, 0 months, 0 days
Research summary
Mesenchymal stromal cells (MSC) have been demonstrated in the literature to have potentially beneficial effects in controlling immune responses, as well as the ability to become several different cell types. The SNBTS wish to harness these properties to generate a cellular therapeutic for a number of potential clinical uses including use alongside pancreatic islets in the treatment of Type 1 Diabetes, and to promote healing of complex bone fractures. To this end, we previously undertook a successful study into the isolation and expansion of MSC from a variety of sources, including Wharton’s jelly from umbilical cord tissue. We now wish to follow on from this study, and develop clinically acceptable methods for deriving, expanding and banking these cells.
REC name
West of Scotland REC 5
REC reference
18/WS/0189
Date of REC Opinion
10 Oct 2018
REC opinion
Favourable Opinion