Depra-T2: Deprescribing Intervention for Older Adults with T2D Ver 1.0
Research type
Research Study
Full title
Using a co-design approach to inform person-centred deprescribing for older adults with Type 2 Diabetes: a qualitative study exploring patient and healthcare professional perspectives
IRAS ID
359273
Contact name
Kirsty
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
0 years, 7 months, 30 days
Research summary
Diabetes is a long-term condition characterised through increased blood glucose levels as a result of the body not being able to make enough insulin or can't use it effectively, or both. Due to the long-term effects of hyperglycaemia (high blood sugar), it can lead to certain long-term complications and damage of various organs such as the heart, kidneys, nerves, eyes, and blood vessels.
Hyperglycaemia and and long-term diabetes especially Type 2 diabetes are linked to onset and severity of frailty which leads to them becoming physically weaker and more susceptible to health problems. Diabetes-related complications can also reduce physical activity, affect memory, and cause damage to major organs. Older people with diabetes often deal with multiple health conditions and are at higher risk of complications. (Abd Ghafar et al., 2022).
There is a need for further research to explore deprescribing interventions as a strategy to optimise medication management, reduce adverse events, costs, and improve quality of life for older adults diagnosed with Type 2 Diabetes.
This study will focus on the development phase of the intervention to understand perspectives on deprescribing from healthcare professionals (HCPs) and patients. This is to ensure that the intervention developed in later stages aligns with the needs, preferences, and experiences of this vulnerable group.The population of interest are older people with diabetes (and their family member/carer).
This study aims to contribute to safer medication prescribing practices by developing an intervention involving stakeholders such as patients, carers, and healthcare professionals, ultimately supporting better healthcare outcomes.
By obtaining the insights from both healthcare professionals and patients through interviews and focus groups, we can carry out this study by using their feedback to co-design a deprescribing intervention. A range of data collection methods such as semi-structured interviews, focus groups and co-design workshops with HCPs and patients will be used.
REC name
South Central - Berkshire B Research Ethics Committee
REC reference
25/SC/0359
Date of REC Opinion
18 Nov 2025
REC opinion
Further Information Favourable Opinion