Dentine erosion using 1% and 5% NaOCl following 17% EDTA VERSION 1
Research type
Research Study
Full title
Dentine erosion using 1% and 5% sodium hypochlorite as a final rinse following 17% EDTA: A SEM quantitative analysis
IRAS ID
279950
Contact name
Michael Horrocks
Contact email
Sponsor organisation
University of Chester
Clinicaltrials.gov Identifier
RESC1219-1009, FH&SC confirmation of scientific merit
Duration of Study in the UK
0 years, 5 months, 10 days
Research summary
Tooth may require root treatment in order to save the tooth. These procedure relies on mechanical instrumentation and irrigation within the canal of a tooth with the use of various irrigants. The literature does not define an ideal protocol for the irrigation sequence. The advocated method stated by the American Association of Endodontists is irrigation using 17% liquid EDTA for no longer than one minute followed by a final rinse with NaOCl. Prior research has established this protocol is essential for healing, however research has highlighted the detriment this protocol has on dentine, the structure of the tooth operated on.
The aim of this study is to determine if using differing concentrations of sodium hypochlorite, as a final rinse, subsequent to the use of 17% EDTA, will impact on the degree of dentine erosion within the root of prepared canals in extracted adult teeth. This could reflect clinical scenarios where practitioners are faced with the predicament of making clinical decisions on the irrigation sequence to provide the most favourable outcome in terms of healing, with no or minimal detriment to the structure and strength of the tooth.The irrigation sequences that will be investigated are 17% liquid EDTA followed by no rinse, saline rinse, 1% sodium hypochlorite and 5% sodium hypochlorite.
REC name
South Central - Hampshire B Research Ethics Committee
REC reference
20/SC/0122
Date of REC Opinion
4 May 2020
REC opinion
Further Information Favourable Opinion