Dental pulp cells for auditory and peripheral nerve regeneration
Research type
Research Study
Full title
The use of dental pulp cells for auditory and peripheral nerve regeneration
IRAS ID
173321
Contact name
Oscar Omar Solis Castro
Contact email
Sponsor organisation
Sheffield Teaching Hospital NHS Foundation Trust
Duration of Study in the UK
3 years, 7 months, 3 days
Research summary
The overall aim of this project is to evaluate the potential use of dental pulp cells for the treatment of deafness and peripheral nerve injury. Dental pulp is found inside each tooth and it consists of soft tissues, like nerves and blood vessels. A number of cells can be found in the dental pulp known as dental pulp cells (DPC). These DPCs may include i) dental pulp stem cells (stem cells are cells that have the potential to become a variety of cell types), ii) glial cells (cells that support the nerves), iii) odontoblast progenitors (specialized tooth cells). Due to the intrinsic capacity of these DPCs we believe that they have important advantages for treating deafness and peripheral nerve injuries. We would like to explore such advantages further for their use in future regenerative therapies.
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
15/YH/0308
Date of REC Opinion
29 Jun 2015
REC opinion
Favourable Opinion