Defining CRPS following TKR surgery V 1.2
Research type
Research Study
Full title
A prospective cohort observational study to define the incidence of Complex Regional Pain Syndrome following Total Knee Replacement according to the Budapest criteria.
IRAS ID
242343
Contact name
Ben Waterson
Contact email
Sponsor organisation
Royal Devon & Exeter NHS Foundation Trust (Wonford)
Duration of Study in the UK
0 years, 9 months, 16 days
Research summary
Some patients develop a complex type of pain after having total knee replacement surgery that we cannot explain. This is called CRPS (Complex Regional Pain Syndrome), and is an exaggerated response to an injury or surgery. This pain is complex to describe, but in short the pain experienced is much worse than we would expect given the injury sustained or surgery performed. CRPS has been reported to occur following total knee replacement surgery, however the criteria used to diagnose this condition have been updated since these reports were published.
Patients can experience a lot of pain following knee replacement surgery, particularly at an early stage, and it is possible for normal pain symptoms to be confused with a more complex type of pain (CRPS). The treatments of these two types of pain is very different, and an incorrect diagnosis could have a negative effect on the overall outcome a patient received following knee replacement surgery.
We do not know how common or rare Complex Regional Pain Syndrome is following total knee replacement surgery according to current criteria used to diagnose this condition, and this is what we are investigating. This will be achieved though performing assessments according to the specific criteria required to diagnose this condition, together with administering questionnaires to patients to assess their pain.
REC name
South Central - Oxford A Research Ethics Committee
REC reference
18/SC/0288
Date of REC Opinion
24 May 2018
REC opinion
Further Information Favourable Opinion