DECODE (V1)
Research type
Research Study
Full title
Development and Evaluation of Interventions in People with Subjective Cognitive Decline
IRAS ID
201727
Contact name
Elizabeth Coulthard
Contact email
Sponsor organisation
University of Bristol
ISRCTN Number
ISRCTN16149416
Clinicaltrials.gov Identifier
Duration of Study in the UK
1 years, 8 months, 1 days
Research summary
Can people with Subjective Cognitive Decline benefit from specific interventions?
The term Subjective Cognitive Decline (SCD) describes any individual expressing concerns about his/her memory. Prior research has shown that SCD may serve as an indicator of preclinical Alzheimer’s disease. However, SCD is also considered as a common complaint which can be caused by normal ageing or psychological factors, such as depression or health anxiety.
At present, there is little to offer to these people in terms of support or treatment because services are focused on people who already have a diagnosis of dementia. It is likely that appropriate intervention for these people could provide significant benefits with regard to maximising their memory and well-being.
In this study the aim is to identify people who are over 45 years old and express memory concerns, but have not received any diagnosis of dementia. The Research Team wants to describe their characteristics and examine whether they could benefit from specific non-pharmacological interventions. These interventions will be delivered as online courses for 4 weeks and will include: a mindfulness meditation course (www.bemindfulonline.com) and a novel course regarding lifestyle choices (www.lifestylefactorsinterventions.com - please refer to the protocol and documents attached). There is also going to be a third group of participants who will act as control group and receive no intervention at the time of testing. This group though, will be offered the lifestyle course right after the end of the final assessment.
The participants’ memory and psychological aspects (like anxiety and stress levels) will be assessed 3 times: before assigning them to one of the interventions (or the no intervention group), right after the end of the course and finally 6 months upon its completion.
REC name
South West - Central Bristol Research Ethics Committee
REC reference
16/SW/0328
Date of REC Opinion
9 Jan 2017
REC opinion
Further Information Favourable Opinion