De-Label Me

• Research type

  Research Study

• Full title

  Evaluating the feasibility of high-volume, low-risk penicillin allergy de-labelling to maximise efficiency in a resource-limited setting

• IRAS ID

  346277

• Contact name

  Joshua Gladman

• Contact email

  joshua.gladman@uhs.nhs.uk

• Sponsor organisation

  University Hospital Southampton NHS Foundation Trust

• Clinicaltrials.gov Identifier

  NCT06532448

• Duration of Study in the UK

  1 years, 0 months, 1 days

• Research summary

  Plenty of studies have now established the safety of low-risk penicillin allergy de-labelling, but few have addressed how to organise de-labelling at the clinic level. This study will test the real world practicalities of running a de-labelling clinic optimised for maximum patient volume. The sheer number of patients with a penicillin allergy label, in contrast to relatively few allergy centres, makes demonstrating that such an approach can work extremely important for future antimicrobial stewardship.

• REC name

  London - City & East Research Ethics Committee

• REC reference

  24/PR/0998

• Date of REC Opinion

  15 Aug 2024

• REC opinion

  Favourable Opinion